Cornelissen L, et al. - Researchers performed this study to investigate the links between end-tidal sevoflurane (ETsevoflurane) concentration, age and frontal electroencephalographic (EEG) spectral properties in predicting recovery of clinical–behavioural signs during emergence from sevoflurane in children 0 to 3 years of age, with and without exposure to nitrous oxide, presuming that clinical signs occur sequentially during emergence, and that for infants aged more than 3 months, changes in alpha EEG power are correlated with clinical–behavioural signs. They reported a sequential occurrence of several clinical signs during emergence, independent of exposure to nitrous oxide. A poor correlation of eye position with other clinical signs or ETsevoflurane was also observed. Furthermore, it was observed that in children more than 3 months, EEG spectral characteristics may aid prediction of clinical–behavioural signs.