de Bruijn TM, de Groot IB, Miedema HS, et al. - Researchers conducted this systematic review and meta-analyses with the aim to determine the clinical relevance of epidural steroid injections (ESIs) for patients with lumbosacral radicular syndrome (LRS). They identified 17 for inclusion in this work. The analyses yielded insufficient evidence supporting the clinical relevance of ESIs for patients with LRS at any follow-up moment. Hence, there is reason to continue the current daily practice of ESIs for patients with LRS. They suggest the necessity for performing high-quality studies using a predefined clinical success to determine potential clinically relevant effects of ESIs.