Putman JM, Zhang L, Gregg AR, et al. - Researchers aimed to determine the clinical pregnancy rates among women who had absolute uterine-factor infertility and underwent in vitro fertilization using good-quality, expanded-blastocyst-stage, euploid embryos following uterus transplantation. In this cohort observational study, they included 20 women who underwent uterus transplantation over 3 years. Of these women, 14 had successful transplants and were followed prospectively for a median of 14.1 months (range, 11–34.8 months). Single embryo transfer of a warmed, good-quality, euploid, expanded blastocyst was performed in all 14 individuals with successful transplants and at least 1 documented clinical pregnancy within the uterus was reported among them. The first embryo transfer resulted in clinical pregnancy in 71.4%. Overall findings suggest that these women can achieve high clinical pregnancy rates. In this study, the time interval from uterus transplantation to embryo transfer was reduced by at least 50% and the interval from uterus transplantation to clinical pregnancy was reduced by > 6 months compared with prior studies. This strategy may allow shortening of the time from transplant to clinical pregnancy and hence allow reduction in patient exposure to immunosuppressant therapies.