Loke BN, et al. - Researchers examined Asian and non-Asian patients with Wilms tumor, to figure out the disparities regarding clinicopathological, and loss of heterozygosity (LOH) profile and survival outcomes between these patient populations. They performed a retrospective review of clinical charts and histological slides from patients with malignant renal tumors over a period of 20 years, and determined 1p36 and 16q21-22 LOH in formalin-fixed paraffin-embedded (FFPE) specimens by means of a genotyping assay. Thereafter, they performed comparisons of these characteristics between Asian and non-Asian patients. They found that, although Asian patients had similar nodal metastasis and LOH rates as noted among non-Asian patients but the former had fewer unfavorable histology tumors, lower-stage disease, and better survival outcomes.