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Clinical insight, cognitive insight and metacognition in psychosis: Evidence of mediation

Journal of Psychiatric Research May 28, 2021

Lysaker PH, Chernov N, Moiseeva T, et al. - As per considerations, an interactive network of disturbances in different elements of self-awareness define schizophrenia. Herein, researchers investigated the correlation between disturbances in two forms of awareness: cognitive insight and clinical insight by exploring whether their relationship is mediated by a third form of larger awareness: metacognition. In Moscow, Russia, 41 outpatients with schizophrenia and 37 outpatients with early episode psychosis were assessed as participants. In mediation analyses, overall metacognitive capacity significantly mediated the relationship between the self-reflection domain of cognitive insight and clinical insight after accounting for the effects of positive symptoms and verbal memory. In addition, positive symptoms were a significant mediator between the cognitive insight self-reflection domain and clinical insight. Overall findings suggest that reductions in some forms of ability to reflect upon one’s thinking may lower the ability to form complex and integrated ideas of oneself and others, resulting in less coherent and complete accounts of the experience of schizophrenia.

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