Shivaprasad C, et al. - The factors related to abnormal electrochemical skin conductance (ESC) were determined in patients with type 2 diabetes mellitus (T2D) and early diabetic peripheral neuropathy (DPN). A high prevalence of sudomotor dysfunction in patients with T2D, especially in those with DPN, was shown. The connection between various diabetes-related factors and lower ESC values was established, suggesteing a link between chronic hyperglycemia and sudomotor function. Furthermore, a strong relationship was discovered between foot deformities and ESC abnormalities. Therefore, the factors associated with DPN appeared to be relevant to sudomotor dysfunction.