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Clinical characteristics of people with cystic fibrosis and frequent fungal infection

Pediatric Pulmonology Oct 28, 2021

Poore TS, Meier M, Towler E, et al. - Via this retrospective study, researchers sought to characterize people with cystic fibrosis (CF) with frequent detection of fungi from airway samples and describe their clinical outcomes.

  • A total of 294 individuals meeting the inclusion criteria were identified; 62% were classified as rare and 38% as frequent fungi during baseline.

  • Observations revealed frequent occurrence of P. aeruginosa and S. maltophilia co-infection in correlation with fungal infection in CF; this was observed even in those without allergic bronchopulmonary aspergillosis (ABPA).

  • Worse outcomes are recorded in individuals with frequent fungi and ABPA, indicating the potential contribution of fungi to CF pulmonary disease.

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