Okike IO, et al. - In infants < 90 days of age with bacterial meningitis, researchers described the clinical characteristics and risk factors associated with poor outcomes via a prospective, enhanced, national population-based active surveillance of these patients in the UK and Ireland between July 2010 and July 2011. The findings demonstrated that the classic features of meningitis were uncommon in these patients. They found that the presentation in young infants was often nonspecific, with only half of the cases presenting with fever. Temperature instability, seizures, cerebrospinal fluid protein greater than the median concentration, and pneumococcal meningitis were independently associated with serious central nervous system complications; prematurity, low birthweight, coma at presentation, and pneumococcal meningitis were independently associated with death.