Nour S, et al. - Researchers here propose a new therapeutic approach for managing sudden cardiac arrest (SCA) in a more effective and secure manner compared with current cardiopulmonary resuscitation (CPR) methods. They identify that a circulatory flow restoration (CFR) device can induce shear stress-mediated endothelial function to restore microcirculation and cellular metabolism. This seems a cost-effective method, predisposes to return of spontaneous circulation in case of SCA, adaptable for all age groups, in public and hospital environments.