Yu H, et al. - Considering the multiple studies have suggested circulating microRNAs (miRNAs) could be promising biomarkers for detecting of lung cancer (LC) early, researchers systematically and comprehensively summarized published articles investigating circulating miRNA candidates for LC detection. They included 17 studies evaluating 35 circulating miRNA markers and 19 miRNA panels in serum or plasma. Findings suggest a potential utility of circulating miRNAs as markers for LC detection and as promising candidates for general cancer screening.