Porter C, et al. - Researchers performed a meta-analysis in order to better appreciate the extent and consistency of the association between childhood adversity and borderline personality disorder (BPD) across case-control, epidemiological and prospective cohort studies. They identified 97 studies that compared BPD to non-clinical (k = 40) and clinical (k = 70) controls. Meta-analysis of case-control studies indicated 13.91 (95% CI 11.11-17.43) times higher likelihood to report childhood adversity among individuals with BPD than non-clinical controls. When considering retrospective cohort and epidemiological studies, this effect was smaller. Across adversity subtypes, significant findings were reported, with emotional abuse and neglect demonstrating the largest effects. Relative to individuals from other psychiatric groups, those with BPD had 3.15 times more likely to report childhood adversity. These findings emphasize considering childhood adversity when treating people diagnosed with BPD.