Sozer V, et al. - This study probed into the associations of serum C-reactive protein(CRP), pentraxin-3(PTX-3), procalcitonin(ProCT), interleukin-33(IL-33) and its soluble receptor ST2 (sST2) with severity of obstructive sleep apnea syndrome (OSAS) and, their utility as biomarkers. Findings suggested that reflecting inflammatory state in OSAS patients, PTX-3 can serve as a new indicator. OSAS patients could exhibit more hypoxic state during sleep and, those patients displayed higher PTX-3 level and a negative correlation between PTX-3 and minimum SaO₂, possibly explaining that PTX-3 levels can increase with the severity of disease. Overall, findings reported that PTX-3 as an inflammatory biomarker may play a crucial role as an indicator of syndrome severity in OSAS.