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Causative agents and outcome of spontaneous bacterial peritonitis in cirrhotic patients: Community-acquired vs nosocomial infections

BMC Infectious Diseases May 30, 2019

Ding X, et al. - Researchers compared nosocomial spontaneous bacterial peritonitis (SBP) vs community-acquired SBP regarding the microbiological features, drug resistance, and treatment results. In this retrospective study, 334 patients (155 patients with nosocomial SBP and 179 with community-acquired SBP) from Beijing Youan Hospital, China, were studied. On reviewing the medical records of these patients and analyzing their clinical and laboratory data, it was noted that the major pathogens involved in SBP in cirrhotic patients were gram-negative bacteria. They identified greater drug resistance in strains isolated from patients with nosocomial SBP vs those isolated from patients with community-acquired SBP. A poorer outcome was noted in correlation with nosocomial SBP vs community-acquired SBP. They recommend considering the acquisition site of infection and the local epidemiological situation when choosing drug treatments.

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