Islam SJ, Kim JH, Topel M, et al. - Researchers here describe the MECA (Morehouse‐Emory Center for Health Equity) Study which was planned to determine the multilevel exposures that add to “resilience” ( a concept that some people have good cardiovascular health outcomes even in the presence of cardiovascular risk factors) in the face of risk for poor cardiovascular health in blacks in the greater Atlanta, GA, metropolitan area. For this purpose, they used census tract data. They performed telephone surveys among more than 1,400 people from these census tracts, and thereafter, they undertook a clinical study with ≈500 people. Also, the American Heart Association's Life Simple 7 measure was employed to evaluate ideal cardiovascular health metrics. Finally, they recruited and randomized overall 150 people with low Life Simple 7 to a behavioral mobile health (eHealth) plus health coach or eHealth only intervention. These people were observed for improvement. Overall, socioenvironmental as well as individual behavioral measures that promote resilience to cardiovascular disease in blacks are being identified via the evaluation of biological, functional, and molecular mechanisms in this study.