Cheong JLY, Haikerwal A, Wark JD, et al. - In view of the reports inscribing possible predictive value of being born extremely preterm (EP; < 28 weeks’ gestation) or extremely low birthweight (ELBW; < 1000 g birthweight) for raised cardiometabolic risk in adulthood, researchers here compared 165 adults born EP/ELBW and 127 controls at age 25 years, drawn from a prospective longitudinal cohort study, with respect to their cardiovascular health profiles. Further, they examined early life associations of cardiovascular health in the EP/ELBW group. Less favorable cardiovascular health profiles were observed among adults born EP/ELBW vs controls; individually for abdominal visceral fat, blood pressure, exercise capacity, and fasting glucose and overall. Male gender was noted to be predictive of unfavorable abdominal visceral fat, blood pressure and fasting glucose, and favorable exercise capacity. Greater increases in weight Z scores between 2 and 8, and 8 and 18 years were noted to be predictive of less favorable profiles of exercise capacity and visceral fat. They suggest undertaking longer-term follow-up as critical to ascertain the cardiovascular sequelae of adults born EP/ELBW.