Grandi SM, et al. - In this systematic review of 84 studies with 28,993,438 patients followed for a median of 7.5 years postpartum, researchers assessed subsequent cardiovascular (CVD) disease in relation to a wide range of pregnancy complications including hypertensive disorders of pregnancy, placental abruption, preterm birth, gestational diabetes mellitus, low birth weight, small-for-gestational-age birth, stillbirth, and miscarriage. They identified relevant studies published from inception to September 22, 2017 in PubMed, MEDLINE and EMBASE (via Ovid), CINAHL, and the Cochrane Library. They generated pooled odds ratios and 95% intrinsic confidence intervals via likelihood ratio meta-analyses. Women with gestational hypertension, preeclampsia, placental abruption, preterm birth, gestational diabetes mellitus, and stillbirth were found to have the highest risk of CVD. They noted a steady trend for low birth weight and small-for-gestational-age birth weight, but not miscarriage.