Cardiac effects of CPAP treatment in patients with obstructive sleep apnea and atrial fibrillation
Journal of Interventional Cardiac Electrophysiology Nov 15, 2018
Abumuamar AM, et al. - Given that obstructive sleep apnea (OSA) has been established as an independent risk factor for the development and progression of atrial fibrillation (AF), researchers investigated how continuous positive airway pressure (CPAP) treatment in patients with OSA and AF influences heart rate and atrial and ventricular ectopy. OSA was defined as an Apnea-Hypopnea-Index (AHI) ≥ 5/hour. They performed ambulatory sleep monitoring on consecutive patients with AF. Among the 100 patients with AF included in the final analysis, 85% received a diagnosis of cancer. In-laboratory CPAP titration study was completed by treated patients. At baseline and at 3 and 6 months after CPAP treatment, a 24-hour electrocardiogram Holter was performed. Compared with baseline, patients with AF and OSA had significantly decreased atrial and ventricular ectopy count/24 hour at 3 and 6 months of CPAP treatment.
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