Thomson ZO, et al. - The aim of this study was to present a systematic review investigating the effectiveness of weight gain prevention interventions among women with breast cancer. The study findings suggested that weight gain can be prevented in women with breast cancer undergoing chemotherapy.

Methods

• For this investigation, completed and ongoing trials assessing a behaviourally based dietary intervention with or without physical activity and with a focus on weight gain prevention during treatment for breast cancer were reviewed.
• After that, weight change and body composition data were extracted.
• Finally, within-group weight change of ±1 kg and between-group (intervention versus control) weight difference of ≥2 kg were characterized as successful weight gain prevention.

Results

• According to the findings obtained, 5 completed trials (seven intervention arms) and 5 ongoing trials were identified.
• Completed trials only selected premenopausal or premenopausal and postmenopausal women.
• Within-group weight gain was prevented in 2 intervention arms, 2 arms achieved weight loss and 3 arms reported weight gain.
• Of the 5 comparisons with control groups, 2 reported significant differences in weight change between groups.
• Ongoing trials will give additional confirmation on longer-term results, cost-effectiveness and blood markers.