DeBaun MR, et al. - Experts intended to contrast the stabilization techniques for large distal femoral defects. The hardest construct in axial and torsional loading, as well as the toughest in torque to failure, was the calcium phosphate cement-filled defect with a locked plate. Nevertheless, this variation only reached importance relative to all other groups in torque to failure testing. In both axial and torsional stiffness testing, the calcium phosphate cement-filled defect with a locked plate was significantly stiffer vs three of the four other groups. Hence, under time zero testing conditions, calcium phosphate cement, with or without the addition of locked plate fixation, may give advanced construct stability.