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Burden of recurrent pericarditis on health-related quality of life

The American Journal of Cardiology Dec 16, 2020

LeWinter M, Kontzias A, Lin D, et al. - Researchers analyzed patients with recurrent pericarditis (RP), to determine health-related quality of life (HRQOL) and work productivity in this patient group. From a centralized recruitment database for the rilonacept Phase 2/3 clinical trials, adult patients were selected by applying inclusion criteria (confirmed RP diagnosis and ≥ 1 recurrence within the previous 12 months). The survey was completed by 83 patients (55% women, average age  =  49.3 years). At the time of survey completion, the median time since pericarditis diagnosis was 3.0 years; ≥3 recurrences were encountered by 49% in the previous 12 months. The average T-scores for Patient-Reported Outcomes Measurement Information System physical and mental health were reported to be 37.6 and 42.8, respectively, vs 50 in the general population. Overall, findings revealed that a high number of recurrences occurred in patients with RP, along with development of severe symptoms that substantially decreased their HRQOL as well as work productivity.

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