Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia: A multinational point prevalence study of hospitalised patients
European Respiratory Journal Jul 12, 2018
Restrepo MI, et al. - Researchers evaluated the multinational burden and specific risk factors related to P. aeruginosa-community-acquired pneumonia (CAP) by examining 3193 patients in 54 countries with confirmed diagnosis of CAP that underwent microbiological testing at admission. The reported prevalence of P. aeruginosa and antibiotic-resistant P. aeruginosa-CAP was 4.2% and 2.0%, respectively. The rate of P. aeruginosa CAP was estimated to be 67% in patients with prior infection/colonisation due to P. aeruginosa and at least one of the three independently associated chronic lung diseases [i.e., tracheostomy, bronchiectasis and/or very severe COPD]). Overall, a low multinational prevalence of P. aeruginosa-CAP was reported. The identified risk factors may be of value in the decision making for empirical antibiotic coverage for CAP patients.
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