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Breast MRI for prediction of lymphovascular invasion in breast cancer patients with clinically negative axillary lymph nodes

European Journal of Radiology Sep 03, 2018

Igarashi T, et al. - In invasive breast cancer patients diagnosed with clinically negative axillary lymph nodes (LNs) preoperatively, researchers retrospectively evaluated magnetic resonance imaging (MRI) findings that have predictive value for lymphovascular invasion (LVI). For this investigation, they involved 140 lesions of 140 subjects who had preoperative breast MRI and breast surgery, without axillary LN dissection. In patients aged ≤ 55, tumor apparent diffusion coefficient (ADC) value, peritumoral ADC value, and peritumor-tumor ADC ratio were predictive MRI findings for LVI. The most significant predictor for LVI was tumor ADC value. Findings revealed that, for tumor ADC value, inter-observer agreement was substantial.

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