Katalinic A, et al. - Researchers determined the impact of the implementation of the German mammography screening program on breast cancer (BC) incidence, age and stage specific incidence and BC mortality during ten years after implementation. They analyzed data on 323,719 breast cancer patients as well as official mortality data from 1998 to 2016 for almost the whole of Germany. Comparison of incidence and mortality rates was performed for prescreening time period (2003/04) and the latest available data (2013/14 and 2015/16 respectively). Since they found distinctly unfavorable corresponding trends in non-exposed age groups, the implementation of the national mammography screening program was most likely held responsible for the observed decrease in the late stage BC incidence and BC mortality in the screening exposed age groups in Germany. These positive influences are obtained at the expense of a moderate occurrence of overdiagnosis, particularly by a sharp rise of in situ cancers.