Stovezky YR, Romanski PA, Bortoletto P, et al. - Researchers conducted a retrospective cohort study with the aim to assess the correlation between BMI and embryo aneuploidy and mosaicism in a cohort of patients undergoing in vitro fertilization (IVF) with trophectoderm biopsy for preimplantation genetic testing for aneuploidy (PGT-A) employing next-generation sequencing technology. They identified the patients undergoing their first IVF cycle with trophectoderm biopsy and PGT-A at their center and stratified them according to the World Health Organization’s BMI classification: normal weight (18.5–24.9 kg/m², n = 1,254), overweight (25–29.9 kg/m ², n = 351), and obese (≥ 30 kg/m², n = 145). Findings from this large cohort of patients undergoing IVF with PGT-A indicated no correlation of BMI with the number or proportion of aneuploid, mosaic, or euploid embryos. This indicates that the negative effect of excess weight on reproductive outcomes was independent of the ploidy status of the embryo cohort.