Li Y, Chen Z, Zeng R, et al. - A significant correlation of bladder neck angle (BNA) with lower urinary tract symptoms and urinary flow rate was found in patients suffering from benign prostatic hyperplasia (BPH). Findings indicate a likely essential role of BNA in the pathogenic mechanism of BPH and acute urine residual (AUR).

• This cohort with 281 first-visit patients was used to assess the impact of the funnel-shaped structure of the bladder neck in BPH.

• An independent association of BNA with the peak flow rate (Qmax) and International Prostate Symptom Score (IPSS) was evident.

• Based on severity of prostate symptoms and Qmax, significant differences were seen in the mean BNA, and mean BNA was 85.5°±17.4° and 89.84°±16.31° in those with severe prostate symptoms and a Qmax<10 ml/s (P<0.001 and <0.001, respectively).

• By linear regression, BNA was positively related to the total IPSS (R=0.718) and inversely linked with Qmax (R=0.569).

• Higher mean BNA was detected in patients with AUR vs that in patients without AUR (86.04°±16.36° vs 63.75°±15.14°).