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Birmingham vasculitis activity and chest manifestation at diagnosis can predict hospitalised infection in ANCA-associated vasculitis

Clinical Rheumatology Mar 24, 2018

Yoo J, et al. - The development rate and time, risk factors, predictors, and aetiologies of hospitalised infection in Korean patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) were determined herein. One-, 5- and 10-year hospitalised infection free survival rates were 85.1, 77.9 and 72.7%, respectively. Findings indicated only chest manifestation at diagnosis was remarkably related to hospitalized infection. As per the data, BVAS at diagnosis ≥ 20.5 and chest manifestation at diagnosis were independent predictors of hospitalised infection during the gap-time. Most common infectious etiology was bacterial pneumonia, followed by a fungal infection including aspergillosis. Hospitalised infection during the gap-time could be predicted by BVAS and chest manifestation at diagnosis.
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