Biochemical characteristics and clinical result of bone marrow-derived fibrin clot for repair of isolated meniscal injury in the avascular zone
Arthroscopy Jun 03, 2021
Hashimoto Y, Nishino K, Orita K, et al. - The present study was performed to characterize bone marrow aspirate-derived fibrin clot (BMA clot) and assess the clinical result of meniscal repair with a BMA clot for isolated meniscal injury in the avascular zone. Researchers examined blood counts of total leukocytes, platelets, and concentrations of basic fibroblast growth factor, transforming growth factor β, and stromal cell-derived factor 1 with BMA, peripheral blood (PB), BMA clot, and PB clot from five patients treated for meniscal repair. It was shown that in comparison with PB clots, BMA clots had increased levels of cytokines. In this retrospective analysis, findings demonstrated that the rates of clinical failure and anatomical failure after meniscal repair with a BMA clot for isolated avascular meniscal injury were 10% and 6.7%, respectively.
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