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Bioavailability of a dexlansoprazole delayed-release orally disintegrating tablet: Effects of food and mode of administration

Clinical and Experimental Gastroenterology Aug 19, 2017

Kukulka M, et al. – Researchers planned this study to evaluate effects of food, water, and route of administration on the bioavailability of dexlansoprazole 30–mg orally disintegrating tablet (ODT). When administered in the fed and fasted states, the area under the plasma concentration–time curve (AUC) from the dexlansoprazole ODT was equivalent. Regardless of the administration route, equivalent systemic exposure to dexlansoprazole was achieved.
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