Tsay EL, et al. - A total of 27,301 simultaneous-bilateral total knee arthroplasties (TKAs) and 45,419 staged-bilateral TKAs from 2005-2014 were reviewed by the researchers in order to analyze the risks of perioperative complications in TKA, to inform shared decision making. A statistically notable greater adjusted odds of mortality, cardiac events, thromboembolic events, and complications involving the urinary and digestive systems, and a lower adjusted odds of deep knee infection and hematoma were observed in individuals who underwent simultaneous surgery. Out of 14 complications, 13 had overall incidences less than 2% and one outcome had an incidence of 3%. The absolute between-group risk difference for any complication was calculated as 1% or less. Hence, in comparison to staged surgery, simultaneous bilateral TKAs had a statistically significant increased odds of multiple complications. Nevertheless, the absolute risk differences among these options were minimal and the occurrence of any complication was concluded as low.