Bactericidal and virucidal activity of povidone-iodine and chlorhexidine gluconate cleansers in an in vivo hand hygiene clinical simulation study
Infectious Diseases and Therapy May 25, 2018
Eggers M, et al. - The bactericidal and virucidal efficacy of povidone-iodine (PVP-I) 7.5% scalp and skin cleanser, chlorhexidine gluconate (CHG) 4% hand cleanser and the reference hand wash (soft soap) were investigated in 15 healthy volunteers following European Standard EN1499 (hygienic hand wash test method for bacteria), which was adapted for virucidal testing. Observation revealed that against murine norovirus (MNV), PVP-I 7.5% cleanser had greater efficacy than soft soap and CHG 4% cleanser. Against Escherichia coli, both PVP-I and CHG were noted to be superior to soft soap. Applicability of the experimental set-up to future testing for antiviral hand washes was suggested.
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