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Atrial fibrillation in patients with severe mental disorders and the risk of stroke, fatal thromboembolic events and bleeding: A nationwide cohort study

BMJ Open Dec 12, 2017

Sogaard M, et al. - Researchers undertook a comparative inspection of the rates of stroke, fatal thromboembolic events and bleeding in patients with atrial fibrillation (AF) with and without mental disorders. Increased rates of stroke and major bleeding were experienced by patients with AF, with schizophrenia or severe depression compared with matched controls. This increase was greatly attributed to the variations in the prevalence of risk factors for stroke and bleeding, comorbidity and initiation of oral anticoagulant therapy (OAT) during follow-up. Additionally, it was reported that the patients with AF with schizophrenia experienced higher mortality following thromboembolic events than those without mental disorders.
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