Kolarova TR, Gammill HS, Nelson JL, et al. - Researchers performed a case‐control study using prospectively obtained maternal plasma (n = 20 preeclampsia, n = 22 normal) using the in‐house validated prenatal screening assay in order to examine if preeclampsia is linked with alteration in cell‐free DNA (cfDNA) parameters. Findings revealed notably higher total cfDNA in preeclampsia, whereas the placental derived fraction remained similar to healthy pregnancies. In preeclampsia, earlier gestational age at delivery and higher systolic blood pressure were observed in correlation with higher total cfDNA. These findings may indicate that maternal tissue injury induces increased release of cfDNA.