Curtin K, Cannon-Albright LA, VanDerslice J, et al. - In order to determine lifestyle factors related to small-intestine neuroendocrine tumors (SINT) and, ultimately, identify at-risk populations in Utah, researchers examined SINT cases with carcinoid histology (8,240 or 8,241) diagnosed in Utah from 1996 to 2014 without previous history of cancer within 5 years (n = 433). They matched these cases with population controls (1:10 ratio), and estimated the risk of SINT related to tobacco and alcohol in cases vs controls using multivariate logistic regression. Findings revealed that tobacco and alcohol use conferred risk for SINT development, independent of family history. However, the possible contribution of other factors to the development of these tumors was suggested by the observed low rates of smoking and alcohol use in Utah together with observed higher rates of SINT.