Jansson-Knodell CL, White M, Lockett C, et al. - An observational study of US-based adults was conducted with the aim to determine the correlations of food intolerance and type of intolerance with irritable bowel syndrome (IBS), health-related quality of life (QOL), and psychological symptoms.

• Participants were a total of 197 adults with (59 lactose, 61 non-lactose food, 77 lactose plus food intolerance) and 273 adults without intolerance.

• Findings revealed correlation of food intolerance with IBS, anxiety, depression, and reduced health-related QOL; it frequently results in food elimination.

• Following were the frequently reported symptoms of FI: gas (54.2%), abdominal pain (40.2%), and diarrhea (37.3%).

• There were higher rates of IBS, increased psychological symptoms, and poorer QOL among adults with lactose and lactose plus food intolerance.