Associations of Apolipoprotein E ε4 Genotype and Ball Heading With Verbal Memory in Amateur Soccer Players
JAMA Feb 03, 2020
Hunter LE, Freudenberg-Hua Y, Davies P, et al. - Researchers performed a cohort of adult amateur soccer players to ascertain if the APOE ε4 allele and 12-month ball heading exposure are correlated with verbal memory. A sum of 379 amateur soccer players were recruited in the longitudinal Einstein Soccer Study between November 11, 2013, and January 23, 2018. Out of these individuals, 355 were genotyped. Three players were eliminated for reporting extreme levels of heading. Further, Verbal memory was evaluated at each study visit utilizing the International Shopping List Delayed Recall task from CogState. This study implies that the APOE ε4 allele is a risk factor for worse memory performance correlated with higher heading exposure in the prior year, which indicates that evaluating genetic risks may finally play a role in improving safer soccer play.
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