Chen Y, Wang N, Dong X, et al. - This study was attempted to ascertain the relationships of individual amino acids (AAs) with the development of type 2 diabetes (T2DM) in rural Chinese adults. Researchers performed a cohort study including 1199 individuals aged 18 years or older between 2006 and 2008 in a rural community of Deqing, China, a repeated survey was carried out in 2015, and data linkage with the electronic health records system was conducted each year for distinguishing new T2DM cases. They used a high-performance liquid chromatography approach to assess the baseline serum concentrations of 15 AAs. They used Cox proportional hazards models to analyze the relationships between AAs and the risk of incident T2DM. They distinguished a total of 98 new T2DM cases during the follow-up of 12 years on average. The findings revealed that serum proline was correlated with the risk of incident T2DM in rural Chinese adults and might be a potential predictor.