Zhu L., Chen P, Sun X, et al. - A meta-analysis was conducted to investigate the relationships between polymorphisms in the IL-1 gene and the risk of rheumatoid arthritis (RA)/systemic lupus erythematosus (SLE). Researchers carried out to systematically search MEDLINE, Embase, Web of Science, Wanfang, VIP, and CNKI for eligible studies, and 34 relevant studies were finally selected to be eligible for inclusion. This study’s findings demonstrated that IL-1A +4845G/T and IL-1B +3954C/T polymorphisms may affect the risk of RA, whereas IL-1A –889C/T, IL-1B –31T/C, and IL-1B –511C/T polymorphisms may influence the risk of SLE.