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Association of urinary calcium and phosphorus excretion with renal disease progression in type 2 diabetes

Diabetes Research and Clinical Practice Jul 28, 2021

Duan S, Sun L, Zhu H, et al. - This retrospective analysis of 159 T2DM patients with chronic kidney disease (CKD stage G1-G4) was performed to determine the relationship of urinary calcium and phosphorus excretion with chronic kidney disease (CKD) progression in type 2 diabetes mellitus. On the basis of tertiles of 24-h urinary calcium and phosphorus excretion, respectively, patients were classified into three groups. A median of 18.23 months of follow-up revealed composite renal outcomes in 27%. Kaplan-Meier analyses showed significantly lower cumulative renal outcomes in the highest tertile of urinary calcium excretion and phosphorus excretion. Findings revealed that T2DM patients showed reduced risk of CKD progression in relation to higher urinary calcium and phosphorus excretion.

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