Silva NR, Gonçalves CET, Gonçalves DLN, et al. - Receiver operating characteristic (ROC) curve revealed better predictive ability of serum uric acid (SUA) than serum uric acid/creatinine ratio (SUA/SCr) for chronic kidney disease (CKD), and no relation of SUA/SCr with CKD was evident. Infact, increased levels of isolated SUA were found to be linked with CKD and estimated glomerular filtration rate (eGFR). Thus, SUA/SCr use is not advised for CKD prediction in hypertensive patients.

• According to recent studies, SUA/SCr better predicts CKD than SUA isolated.

• This cross-sectional study was performed with hypertensive patients followed-up by the Primary Health Care Service.

• Bivariate and multivariate logistic regression as well as ROC curve were applied.

• Fully adjusted model showed a positive association of SUA with CKD presence (OR = 6.72) and its inverse relation with eGFR.

• SUA/SCr demonstrated a positive relation to eGFR.