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Association of smoking cessation with subsequent risk of cardiovascular disease

JAMA Aug 23, 2019

Duncan MS, et al. - Through an observational cohort study of prospectively collected data from the Framingham Heart Study, which included 8,770 individuals without baseline cardiovascular disease (CVD), researchers assessed the correlation between years since smoking cessation and incident CVD. A total of 2,435 first CVD event were noted over 26.4 median follow-up years. In the pooled cohort, in contrast with current smoking, quitting within 5 years was related to significantly lower rates of incident CVD and a lower risk of incident CVD. Furthermore, compared with never smoking, quitting smoking ceased to be significantly correlated with higher CVD risk between 10 and 15 years following cessation. Thus, smoking cessation was correlated with a significantly lower risk of CVD within 5 years among heavy smokers, with regards to current smokers. Nevertheless, in relation to never smokers, previous smokers’ CVD risk continued to be significantly elevated beyond 5 years following smoking cessation.

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