Feinberg C, Carr C, Zemek R, et al. - In this study, the relationships between commonly used pharmacological interventions and symptom burden reduction among patients with mild traumatic brain injury were explored. Researchers distinguished 23 studies analyzing 20 pharmacological interventions used to mitigate the symptoms associated with mild traumatic brain injury in this systematic review of articles published between 2000 and 2020. This systematic review demonstrated that none of the pharmacological interventions examined were consistently correlated with symptom burden reduction across the studies included in the review, which is likely owing to the limited number of high-quality studies of mild traumatic brain injury; there is a need for implementation of standardized measures to provide comparable clinical evaluations across studies.