Cagney DN, et al. - In patients with brain metastases treated with adjuvant stereotactic radiation, researchers described the relationship and incidence of pachymeningeal seeding with neurosurgical resection. In this cohort study of 1,188 patients, resection has been found to be linked to pachymeningeal seeding but not leptomeningeal disease. Durable salvage of pachymeningeal seeding was not common, but with radiotherapeutic methods, a small percentage of patients attained sustained disease control. According to findings, pachymeningeal seeding beyond the stereotactic radiation field represents a notable oncologic event that often proves hard to salvage in the era of omission of adjuvant whole-brain radiation following neurosurgical resection. However, with radiotherapeutic methods, disease control can be achieved in some patients.