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Association of myocarditis with BNT162b2 messenger RNA COVID-19 vaccine in a case series of children

JAMA Cardiology Dec 16, 2021

Dionne A, Sperotto F, Chamberlain S, et al. - Cardiac imaging findings in children with myocarditis after COVID-19 vaccination are described.

  • A case series of 15 children (14 male patients [93%]; median age, 15 years [range, 12-18 years]) who were hospitalized for management of myocarditis after receiving the BNT162b2 (Pfizer) vaccine.

  • More frequently, boys were affected after the second vaccine dose; ventricular systolic dysfunction was recorded in three cases, and in 12 patients, late gadolinium enhancement was evident on cardiac magnetic resonance imaging.

  • No mortality was recorded, and normal echocardiogram results were recorded in all but 1 patient on follow-up 1 to 13 days after discharge.

  • Overall, there has been a benign short-term course of COVID-19 vaccine-associated myocarditis in children.

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