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Association of metabolic comorbidities with pediatric psoriasis: A systematic review and meta-analysis

Annals of Dermatology Jun 08, 2021

Cho SI, et al. - Researchers intended to determine if there is an association between psoriasis and metabolic comorbidities in pediatric patients by searching articles published in PubMed, EMBASE, and Cochrane Library databases from inception to April 30, 2019. All observational studies that reported the prevalence of obesity or metabolic comorbidities in pediatric psoriasis patients were considered. According to this systematic review and meta-analysis, pooled odds ratios in pediatric patients with psoriasis were 2.40 for obesity, 2.73 for hypertension, 2.01 for diabetes mellitus, 1.67 for dyslipidemia, and 7.49 for metabolic syndrome. Obesity, hypertension, diabetes, dyslipidemia, and metabolic syndrome were significantly more prevalent in pediatric psoriasis patients. In such patients, adequate monitoring and timely management of metabolic comorbidities should be considered.

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