Chlebowski RT, et al. - Researchers investigated the association of a low-fat dietary pattern with breast cancer overall survival (breast cancer followed by death from any cause measured from cancer diagnosis) in this secondary analysis of the Women’s Health Initiative randomized clinical trial that was conducted at 40 US clinical centers enrolling participants from 1993 through 1998. Postmenopausal women with no previous breast cancer and dietary fat intake of greater than 32% by food frequency questionnaire were randomized either to a dietary intervention group, aimed to reduce fat intake to 20% of energy and increase fruit, vegetable, and grain intake or to a usual-diet comparison group. In women who received a diagnosis of breast cancer during the dietary intervention period, an increased overall survival was observed in those in the dietary group. The increase was partially attributed to better survival from several causes of death.