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Association of immunosuppressants with mortality of patients with bullous pemphigoid: A nationwide population-based cohort study

Dermatology Jun 22, 2021

Wu CY, Wu CY, Li CP, et al. - Researchers used the National Health Insurance Research Database in Taiwan, to determine if immunosuppressants use was related to decreased mortality in bullous pemphigoid (BP) patients. The immunosuppressant cohort comprised BP patients taking any immunosuppressant for ≥28 days per month for 3 consecutive months. Experts matched (1:4) overall 452 BP patients on immunosuppressants, by age, gender, propensity score of comorbidities, and use of tetracycline, with 1,808 BP patients receiving only corticosteroids. A 22% decreased risk of BP mortality was observed in relation to immunosuppressant use. More substantial impacts were seen in patients aged <70 years, with a 55% decreased risk of mortality.

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