Huang F, et al. - This study including children with a diagnosis of simple asthma or asthma plus allergic rhinitis (AR), investigated the frequency and absolute numbers of different subsets of peripheral blood cells, including CD4⁺ T cells and CD19⁺ interleukin (IL) 10⁺ B regulatory cells (Breg) and their potential association with clinical laboratory measurements in these subjects. In study participants, imbalance of effector T cells and regulatory cells was identified as a contributor to the pathogenesis of airway inflammation of asthma and AR.