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Association of depression and anxiety with cognitive impairment 6 months after stroke

Neurology® Apr 15, 2021

Williams OA, Demeyere N., et al. - In this investigation involving 437 candidates, researchers sought to examine the connections between general cognitive impairment and domain-specific cognitive impairment with depression and anxiety 6 months after a stroke. The sample consisted of patients with confirmed acute stroke from the OCS-Care Study who were selected on stroke wards in a multisite study and followed up at a 6 months after a stroke assessment. Domain-general and domain-specific poststroke cognitive impairment was found to be strongly associated with depressive symptomatology but not with anxiety symptomatology. Six-month poststroke depression was linked with 6-month impairment on the MoCA and all individual domains evaluated by the OCS. Poststroke anxiety was associated with impairment on the MoCA and spatial attention; these associations did not remain significant after controlling for co-occurring poststroke depression.

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