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Association of child abuse and systemic lupus erythematosus in black women during adulthood

Arthritis Care & Research Jun 10, 2021

Cozier YC, Barbhaiya M, Castro-Webb N, et al. - In this study, the association of childhood physical and sexual abuse to risk of systemic lupus erythematosus (SLE) among Black women was explored. Researchers followed 36,152 women from 1995 through 2015 with biennial questionnaires using data from the Black Women’s Health Study. They used Cox proportional hazards regression models to calculate hazard ratios and 95% confidence intervals (95% CIs) for SLE among women exposed to physical or sexual abuse during childhood, controlling for potential confounders. The data imply that sexual and physical abuse during childhood increase SLE risk during adulthood among Black women. There is a need for research to confirm this finding and to understand potential mediating mechanisms.

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