Livne O, Shmulewitz D, Sarvet AL, et al. - Associations between self-reported psychotic disorder and frequent nonmedical cannabis use and cannabis use disorder were demonstrated by analyzing data from the US general population, especially more recent data. These relationships should be considered when monitoring patients and formulating programs.

• Researchers retrieved data of individuals who participated in the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC; 2001–2002; N = 43,093) and NESARC-III (2012–2013; N = 36,309).

• Participants with vs without any nonmedical cannabis use had significantly greater prevalence of self-reported psychotic disorders.

• In 2001–2002, no relation appeared between self-reported psychotic disorders and frequent use or daily/near-daily use.

• However, in 2012 − 2013, self-reported psychotic disorders appeared more common among participants with frequent use and those with daily/near-daily nonmedical cannabis use when compared with nonusers.

• In both surveys, participants with cannabis use disorder had significantly greater prevalence of self-reported psychotic disorders when compared with nonusers.

• No change in the strength of these associations appeared over time.